pbpk modeling tools Search Results


pbpk model toolkit  (Disease Registry)
90
Disease Registry pbpk model toolkit
Schematic overview of the <t>physiologically</t> <t>based</t> <t>pharmacokinetic</t> <t>(PBPK)</t> and signaling pathways for potential use in chemical mixtures assessment. A, Representation of the PBPK steps used. Recoding, evaluation, and application of the published (B) toluene, ethylbenzene, and xylene (TEX) PBPK model. B, Toluene, ethylbenzene, and xylene pathways analysis. Representation of the chemical/gene/disease’s interactions component. Use of published high-throughput analysis, toxicogenomic databases, and systems biology platforms to understand pathways impacted by chemical mixtures. C, PBPK/PD and signaling pathways. Representation of exploring the A and B components and future connecting directions.
Pbpk Model Toolkit, supplied by Disease Registry, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pbpk model toolkit/product/Disease Registry
Average 90 stars, based on 1 article reviews
pbpk model toolkit - by Bioz Stars, 2026-04
90/100 stars
  Buy from Supplier
pbpk modelling tool simcyp version 20  (Simcyp)
90
Simcyp pbpk modelling tool simcyp version 20
Schematic overview of the <t>physiologically</t> <t>based</t> <t>pharmacokinetic</t> <t>(PBPK)</t> and signaling pathways for potential use in chemical mixtures assessment. A, Representation of the PBPK steps used. Recoding, evaluation, and application of the published (B) toluene, ethylbenzene, and xylene (TEX) PBPK model. B, Toluene, ethylbenzene, and xylene pathways analysis. Representation of the chemical/gene/disease’s interactions component. Use of published high-throughput analysis, toxicogenomic databases, and systems biology platforms to understand pathways impacted by chemical mixtures. C, PBPK/PD and signaling pathways. Representation of exploring the A and B components and future connecting directions.
Pbpk Modelling Tool Simcyp Version 20, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pbpk modelling tool simcyp version 20/product/Simcyp
Average 90 stars, based on 1 article reviews
pbpk modelling tool simcyp version 20 - by Bioz Stars, 2026-04
90/100 stars
  Buy from Supplier

Image Search Results


Schematic overview of the physiologically based pharmacokinetic (PBPK) and signaling pathways for potential use in chemical mixtures assessment. A, Representation of the PBPK steps used. Recoding, evaluation, and application of the published (B) toluene, ethylbenzene, and xylene (TEX) PBPK model. B, Toluene, ethylbenzene, and xylene pathways analysis. Representation of the chemical/gene/disease’s interactions component. Use of published high-throughput analysis, toxicogenomic databases, and systems biology platforms to understand pathways impacted by chemical mixtures. C, PBPK/PD and signaling pathways. Representation of exploring the A and B components and future connecting directions.

Journal: Toxicological sciences : an official journal of the Society of Toxicology

Article Title: Exploring Mechanistic Toxicity of Mixtures Using PBPK Modeling and Computational Systems Biology

doi: 10.1093/toxsci/kfz243

Figure Lengend Snippet: Schematic overview of the physiologically based pharmacokinetic (PBPK) and signaling pathways for potential use in chemical mixtures assessment. A, Representation of the PBPK steps used. Recoding, evaluation, and application of the published (B) toluene, ethylbenzene, and xylene (TEX) PBPK model. B, Toluene, ethylbenzene, and xylene pathways analysis. Representation of the chemical/gene/disease’s interactions component. Use of published high-throughput analysis, toxicogenomic databases, and systems biology platforms to understand pathways impacted by chemical mixtures. C, PBPK/PD and signaling pathways. Representation of exploring the A and B components and future connecting directions.

Article Snippet: The Agency for Toxic Substances and Disease Registry (ATSDR) has developed a PBPK model toolkit, these are being recoded into a single language, Berkeley Madonna ( Emond et al., 2017 ; Mumtaz et al., 2012 ; Ruiz et al., 2010 ) and are validated and evaluated as part of the methods development.

Techniques: Protein-Protein interactions, High Throughput Screening Assay